{"id":19005,"date":"2024-07-01T15:21:32","date_gmt":"2024-07-01T13:21:32","guid":{"rendered":"https:\/\/www.mapeisport.it\/attivita-scientifica\/the-time-course-of-irisin-release-after-an-acute-exercise-relevant-implications-for-health-and-future-experimental-designs\/"},"modified":"2024-08-28T10:43:25","modified_gmt":"2024-08-28T08:43:25","slug":"the-time-course-of-irisin-release-after-an-acute-exercise-relevant-implications-for-health-and-future-experimental-designs","status":"publish","type":"attivita-scientifica","link":"https:\/\/www.mapeisport.it\/en\/attivita-scientifica\/the-time-course-of-irisin-release-after-an-acute-exercise-relevant-implications-for-health-and-future-experimental-designs\/","title":{"rendered":"The time course of irisin release after an acute exercise: relevant implications for health and future experimental designs"},"content":{"rendered":"

Tommasini E1,2,3<\/sup>, Missaglia S1,2<\/sup>, Vago P1,2<\/sup>, Galvani C2,3<\/sup>, Pecci C4<\/sup>, Rampinini E4,5<\/sup>, Bosio A4<\/sup>, Morelli A4<\/sup>, Bonanomi A6<\/sup>, Silvestrini A7<\/sup>, Mordente A7<\/sup>, Tavian D1,2<\/sup><\/p>\n

    \n
  1. Laboratory of Cellular Biochemistry and Molecular Biology, CRIBENS, Universit\u00e0 Cattolica del Sacro Cuore, Milan, Italy;<\/li>\n
  2. Department of Psychology, Universit\u00e0 Cattolica del Sacro Cuore, Milan, Italy;<\/li>\n
  3. Exercise & Sport Science Laboratory, Universit\u00e0 Cattolica del Sacro Cuore, Milan, Italy;<\/li>\n
  4. Human Performance Laboratory, MAPEI Sport Research Center, Olgiate Olona, Italy<\/li>\n
  5. Sport and Exercise Discipline Group, Human Performance Research Centre, Faculty of Health, University of Technology Sydney, Moore Park, NSW;<\/li>\n
  6. Department of Statistical Science, Universit\u00e0 Cattolica del Sacro Cuore, Milan, Italy;<\/li>\n
  7. Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy.<\/li>\n<\/ol>\n

    \"\"<\/p>\n

    Abstract<\/strong><\/p>\n

    This study aimed to analyze the acute impact of exercise on serum irisin levels in 22 young (YA, 24.6 \u00b1 3.5 yrs) and in 12 middle-aged male adults (MA, 54.6 \u00b1 5.7 yrs) 15 min and 24 h after an incremental cycling exercise test to exhaustion. ELISA assay was used for serum irisin detection. Circulating irisin increased significantly from baseline (9.0 \u00b1 2.0 ng\/ml) to 15 min post-exercise (10.2 \u00b1 2.0 ng\/ml, P < 0.001), but the greatest increment was detected after 24 h (13.5 \u00b1 2.5 ng\/ml, P < 0.001) reaching more than 50% of the basal release. Levels were significantly higher in YA (9.7 \u00b1 1.7 to 11.1 \u00b1 1.8 to 14.5 \u00b1 2.2 ng\/ml) than MA (7.6 \u00b1 1.6 to 8.7 \u00b1 1.5 to 11.8\u00b1 2.2 ng\/ml) for all measured time-points (P < 0.05). Nevertheless, MA showed a comparable increase in serum irisin levels when compared to YA. These findings highlight the importance of acute physical exercise as a countermeasure against age-related deterioration of skeletal muscle mass and function in both YA and MA.<\/p>\n

    Eur J Transl Myol, 2024 Jul 1<\/p>\n

    PMID:\u00a038949080\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 PMCID:\u00a0PMC11264220<\/a>\u00a0\u00a0 DOI:\u00a010.4081\/ejtm.2024.12693<\/a><\/p>\n

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